Chemistry in Live Cells

The consortium Chemistry in live cells is funded by Emerging Fields Initiative of the Friedrich-Alexander-Universität Erlangen-Nürnberg since 2017 and additionally by the STAEDTLER^® Stiftung since 2018.

An interdisciplinary team covering fields of organic chemistry (Mokhir, Schatz, Tsogoeva, Jux), pharmacetical chemistry (Heinrich), physical chemistry (Guldi, Heilemann), theoretical chemistry (Beierlein, Clark) and medicine (Prante) is working since 01.01.2017 on the development of chemical bond-forming reactions (C-O, C-S, C-Se, C-C), which are compatible with live cells. These reactions should lead to formation of either drugs or easily detectable (e.g. fluorescent, radioactive) compounds. The results, which can be obtained in this project, can potentially lead to new treatment methods for diseases like cancer and chronic inflammation as well as to novel diagnostic tools.