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Publications

Publications since 01.01.2017 (project start):

  1. T. Fröhlich, A. Kiss, J. Wolfling, E. Mernyak, Á. E. Kulmány, R. Minorics, I. Zupkó, M. Leidenberger, O. Friedrich, B. Kappes, F. Hahn, M. Marschall, G. Schneider, S. B. Tsogoeva. Synthesis of artemisinin-estrogen hybrids highly active against HCMV, P. falciparum, cervical and breast cancer. ACS Med. Chem. Lett.2018, DOI: 10.1021/acsmedchemlett.8b00381
  2. J. Toms, V. Reshetnikov, S. Maschauer, A. Mokhir, O. Prante.* Radiosynthesis of an 18F-fluoroglycosylated aminoferrocene for in-vivo imaging of reactive oxygen species activity by PETJ. Labelled Compounds & Radiopharmaceuticals2018, accepted on 01.10.2018; DOI:10.1002/jlcr.3687.
  3. V. Reshetnikov, S. Daum, C. Janko, W. Karawacka, R. Tietze, C. Alexiou, S. Paryzhak, T. Dumych, R. Bilyy, P. Tripal, B. Schmid, R. Palmisano, A. Mokhir.* ROS-responsive N-alkylaminoferrocenes for cancer cell specific targeting of mitochondriaAngew. Chem. Int. Ed., 2018, 57, 11943-11946. Link: https://doi.org/10.1002/anie.201805955
  4. V. Reshetnikov, J. Hahn, C. Maueröder, C. Czegley, L. E. Munoz, M. Herrmann, M. H. Hoffmann,* A. Mokhir.* Chemical tools for targeted amplification of reactive oxygen species in neutrophils. Frontiers in Immunology, 2018, Aug. 13: 9, 1827; doi: 10.3389/fimmu.2018.01827.
  5. V. Reshetnikov, A. Arkhypov, P. R. Julakanti, A. Mokhir.* A cancer specific oxaliplatin-releasing Pt(IV)-prodrugDalton Trans.2018, 47, 6679-6682.
  6. S. Daum, S. Babiy, H. Konovalova, W. Hofer, A. Shtemenko, N. Shtemenko, C. Janko, C. Alexiou, A. Mokhir, A.* Tuning the structure of aminoferrocene-based anticancer prodrugs to prevent their aggregation in aqueous solution. J. Inorg. Biochem., 2018, 178, 9-17.
  7. C. Fröhlich, C. Reiter, M. E. M. Saeed, C. Hutterer, F. Hahn, M. Leidenberger, O. Friedrich, B. Kappes, M. Marschall, T. Efferth, S. B. Tsogoeva. Synthesis of Thymoquinone–Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents. ACS Med. Chem. Lett., 2018, 9, 534-539.
  8. T. Fröhlich, F. Hahn, L. Belmudes, M. Leidenberger, O. Friedrich, B. Kappes, Y. Couté, M. Marschall,* S. B. Tsogoeva.* Synthesis of artemisinin-derived di/tri-mers and dendrimers, investigation of their activity against P. falciparum and cytomegalovirus, and insights into their mechanisms of action. Chem. Eur. J., 2018, 24, 8103-8113.
  9. A. Çapcı Karagöz, C. Reiter, E.-J. Seo, L. Gruber, F. Hahn, M. Leidenberger, V. Klein, F. Hampel, O. Friedrich, M. Marschall, B. Kappes, T. Efferth, S. B. Tsogoeva.* Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin. Bioorg. Med. Chem. 2018, 26, 3610-3618.
  10. T. Fröhlich, C. Reiter, M. M. Ibrahim, J. Beutel, C. Hutterer, I. Zeitträger, H. Bahsi, M. Leidenberger, O. Friedrich, B. Kappes, T. Efferth, M. Marschall, S. B. Tsogoeva. Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells. ACS Omega, 2017, 2, 2422-2431.
  11. F. E. Held, A. A. Guryev, T. Fröhlich, F. Hampel, A. Kahnt, C. Hutterer, M. Steingruber, H. Bahsi, C. von Bojnicic-Kninski, D. S. Mattes, T. C. Foertsch, A. Nesterov-Mueller, M. Marschall, S. B. Tsogoeva, Facile access to potent antiviral quinazoline heterocycles with fluorescence properties via merging metal-free domino reactions. Nature Communications, 2017, 15071.
  12. C. M. Bock, G. Parameshwarappa, S. Bönisch, W. Bauer, C. Hutterer, M. Leidenberger, O. Friedrich, M. Marschall, B. Kappes, A. Görling, S. B. Tsogoeva. Deeper Insight into the Six-Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products. ChemistryOpen, 2017, DOI: 10.1002/open.201700005.